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Enfortumab vedotin-ejfv

Cat. No. M24619

All AbMole products are for research use only, cannot be used for human consumption.

Enfortumab vedotin-ejfv Structure

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Quality Control & Documentation
Biological Activity

Enfortumab vedotin-ejfv is an anti-Nectin-4 antibody-drug conjugate (ADC) for the management of urothelial carcinoma. Enfortumab vedotin-ejfv is a fully humanized IgG1 antibody conjugated to the microtubule disrupting agent MMAE via a protease-cleavable maleimidocaproylvaline-citrulline linker.

Chemical Information
CAS Number 1346452-25-2
Form Solution
Storage -80°C, protect from light
References

[1] Olivier Cabaud, et al. Mol Cancer Ther. Overcoming Resistance to Anti-Nectin-4 Antibody-Drυg Conjugate

[2] Charlene M Mantia, et al. Expert Rev Anticancer Ther. Enfortumab vedotin-ejfv for the treatment of advanced urothelial carcinoma

[3] No authors listed. Enfortumab Vedotin

[4] Zachery Halford, et al. Ann Pharmacother. Enfortumab Vedotin-ejfv: A First-in-Class Anti-Nectin-4 Antibody-Drυg Conjugate for the Management of Urothelial Carcinoma

[5] Hélène Kaplon, et al. MAbs. Antibodies to watch in 2020

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Keywords: Enfortumab vedotin-ejfv supplier, Antibody-Drug Conjugates (ADCs), inhibitors, activators

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