All AbMole products are for research use only, cannot be used for human consumption.
Endothelin-1 (human, porcine) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin-1 acts through two types of receptors ETA and ETB. ET-1 causes fibrosis of the vascular cells and stimulates production of reactive oxygen species. It is claimed that ET-1 induces proinflammatory mechanisms, increasing superoxide anion production and cytokine secretion.
Sci Rep. 2025 Feb 15;15(1):5626.
Identification of ECE2 signaling in promoting non-small lung cancer progression through ET1/YAP1/MAGEA3 axis
Endothelin-1 (human, porcine) purchased from AbMole
Cytotherapy. 2024 Jul 24.
Human neural stem cells transplanted during the sequelae phase alleviate motor deficits in a rat model of cerebral palsy
Endothelin-1 (human, porcine) purchased from AbMole
| Molecular Weight | 2491.9 |
| Formula | C109H159N25O32S5 |
| CAS Number | 117399-94-7 |
| Solubility (25°C) | Soluble in water |
| Storage | -20°C, dry, protect from light, sealed |
| Related Endothelin Receptor Products |
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| A-127722
A-127722 is A 2, 4-dialarylpyrrolidine-3-carboxylic acid ETA selective endothelin receptor (ET receptor) antagonist with IC50 value of 0.36 nM. |
| Endothelin 1 (swine, human) (TFA)
Endothelin 1 (swine, human) (TFA) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. |
| Atrial Natriuretic Peptide (ANP) (1-28), rat
Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner. |
| [Asn18] Endothelin-1, human
[Asn18] Endothelin-1, human is a peptide. |
| [Lys4] Sarafotoxin S6c
[Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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