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EMD638683 is a highly selective SGK1 inhibitor with an IC50 value of 3 μM.
| Molecular Weight | 364.34 |
| Formula | C18H18F2N2O4 |
| CAS Number | 1181770-72-8 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related SGK Products |
|---|
| SGK1-IN-4
SGK1-IN-4 is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for the research of osteoarthritis. |
| SGK1-IN-3
SGK1-IN-3 is a potent and orally active inhibitor of SGK1. |
| HaloPROTAC-E
HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14). |
| SGK1-IN-2
SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration. |
| SI-113
SI-113 is a SGK1 inhibitor, with an IC50 of 600 nM. SI113 induces autophagy. |
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