SGK Serum and glucocorticoid regulated kinases (SGKs)

Inhibitor

Cat.No.	Name	Information
M11404	EMD638683	EMD638683 is a highly selective SGK1 inhibitor with an IC50 value of 3 μM.
M5325	GSK 650394	GSK650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2, respectively.
M29542	HaloPROTAC-E	HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14).
M28400	SGK1-IN-2	SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration.
M28315	SI-113	SI-113 is a SGK1 inhibitor, with an IC50 of 600 nM. SI113 induces autophagy.
M14535	EMD638683 R-Form	EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.