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Elobixibat

Cat. No. M10815

All AbMole products are for research use only, cannot be used for human consumption.

Elobixibat Structure
Synonym:

A 3309

Price and Availability

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Quality Control & Documentation
Biological Activity

Elobixibat is a potent ileal bile acid transporter (IBAT) inhibitor, IC50 Values were 0.53±0.17 nM (human IBAT), 0.13±0.03 nM (mouse IBAT), 5.8± 1.6 nM (canine IBAT).

Chemical Information
Molecular Weight 695.89
Formula C36H45N3O7S2
CAS Number 439087-18-0
Solubility (25°C) DMSO ≥ 200 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anna Ozaki, et al. Oncologist. Elobixibat Effectively Relieves Chronic Constipation in Patients with Cancer Regardless of the Amount of Food Intake

[2] Lehar Khanna, et al. Aliment Pharmacol Ther. Review article: Elobixibat: a novel treatment for chronic constipation

[3] Daigo Kamei, et al. BMC Gastroenterol. Elobixibat alleviates chronic constipation in hemodialysis patients: a questionnaire-based study

[4] Victor Chedid, et al. Expert Rev Gastroenterol Hepatol. Elobixibat for the treatment of constipation

[5] Banny S Wong, et al. Expert Opin Investig Drugs. Elobixibat for the treatment of constipation

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Keywords: Elobixibat, A 3309 supplier, inhibitors, activators

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