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Edralbrutinib (TG-1701) is a potent, novel, orally active, irreversible BTK inhibitor that selectively inhibits the activation, proliferation, and survival of B cells, and can act on other immune cells, such as macrophages, to influence the autoimmune inflammatory process mediated by B cells and other immune cells, and can be used in the study of optic neuromyelitis optica spectrum disorders (NMOSD).
| Molecular Weight | 489.47 |
| Formula | C26H21F2N5O3 |
| CAS Number | 1858206-58-2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Related BTK Products |
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| BIIB129
BIIB129 is a covalent, selective inhibitor of Bruton's tyrosine kinase (BTK) capable of penetrating the blood-brain barrier. BIIB129 inhibits the activity of BTK by covalently binding to Cys481 in BTK, thereby affecting the function of B cells and myeloid cells. |
| UBX-382
UBX-382 is an orally available proteolysis-targeting chimeras (PROTACs) that target BTK to inactivate B-cell receptor signaling. |
| GDC-0834
GDC-0834 is a potent and selective BTK inhibitor. |
| DD-03-171
DD-03-171 is a BTK, IKFZ1 and IKFZ3 degrader, the BTK IC50 a value of 5.1 nM. |
| N-piperidine Ibrutinib hydrochloride
N-piperidine Ibrutinib hydrochloride is a reversible Ibrutinib derivative. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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