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Edaravone

Cat. No. M2251

All AbMole products are for research use only, cannot be used for human consumption.

Edaravone Structure
Synonym:

MCI-186

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 50  USD50 In stock
500mg USD 45  USD45 In stock
1g USD 50  USD50 In stock
5g USD 55  USD55 In stock
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Quality Control & Documentation
Biological Activity

Edaravone is a radical scavenger and antioxidant which is able to protect against the effects of ischemia, probably by inhibiting the lipoxygenase system. Edaravone is used for treatment of patients with acute brain infarction. Edaravone protects against MPTP-induced neurotoxicity.

Chemical Information
Molecular Weight 174.2
Formula C10H10N2O
CAS Number 89-25-8
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jie Xu, et al. Edaravone Dexborneol Versus Edaravone Alone for the Treatment of Acute Ischemic Stroke: A Phase III, Randomized, Double-Blind, Comparative Trial

[2] Jeremy Shefner, et al. Long-term edaravone efficacy in amyotrophic lateral sclerosis: Post-hoc analyses of Study 19 (MCI186-19)

[3] Hiide Yoshino. Edaravone for the treatment of amyotrophic lateral sclerosis

[4] Manoj Kumar Jaiswal. Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs

[5] R Bhandari, et al. Edaravone: a new hope for deadly amyotrophic lateral sclerosis

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Keywords: Edaravone, MCI-186 supplier, ROS, inhibitors, activators

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