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Econazole nitrate

Cat. No. M3489

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Econazole nitrate Structure
Size Price Availability Quantity
500mg USD 40  USD40 In stock
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Quality Control & Documentation
Biological Activity

Econazole nitrate (Spectazole) is an imidazole class antifungal medication. Econazole nitrate (Spectazole) is used to treat skin infections such as athlete’s foot, tinea, pityriasis versicolor, ringworm, and jock itch. The in vitro activity spectrum of econazole nitrate (Spectazole) is very broad: the dermatophytes, the yeasts, the dimorphic fungi, the aspergilli, the mycetoma causing agents and the Gram-positive bacteria being most sensitive. Guinea-pigs infected with T. mentagrophytes, M. canis or C. albicans and treated topically or orally with econazole, were cured. In each of these tests the activity of econazole was compared with that of different reference drugs. Vaginal candidiasis in rats was cured after oral administration of econazole.

Chemical Information
Molecular Weight 444.7
Formula C18H15Cl3N2O.HNO3
CAS Number 24169-02-6
Form Solid
Solubility (25°C) DMSO 80 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] M G Mostafa, et al. Efficacy of Clotrimazole 1% Solution Compared to Econazole Nitrate 1% + Triamcinolone Acetonide 0.1% Cream in Patient with Otomycosis

[2] Shivani Verma, et al. Transethosomes of Econazole Nitrate for Transdermal Delivery: Development, In-vitro Characterization, and Ex-vivo Assessment

[3] Alan B Fleischer Jr, et al. Econazole Nitrate Foam 1% Improves the Itch of Tinea Pedis

[4] Boni E Elewski, et al. Econazole nitrate foam 1% for the treatment of tinea pedis: results from two double-blind, vehicle-controlled, phase 3 clinical trials

[5] Irina Vennewald, et al. Otomycosis: Diagnosis and treatment

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