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E-982

Cat. No. M14695
E-982 Structure
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Biological Activity

E-982 is a steroid used for the on-line screening of the DNA unwinding element binding protein (DUE-B) immobilized protein column.

Chemical Information
Molecular Weight 473.58
CAS Number 858102-78-0
Storage 2-8°C, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] M K Taneja. Prevention and Rehabilitation of Old Age Deafness

[2] M K Taneja. Modified Bhramari Pranayama in Covid 19 Infection

[3] M K Taneja. Role of Platelet Rich Plasma in Tympanoplasty

[4] M K Taneja. Deafness, a Social Stigma: Physician Perspective

[5] M K Taneja. Preimplantation genetic diagnosis and deafness

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  Catalog
Abmole Inhibitor Catalog




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