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DuP 697 is a potent and selective inhibitor of cyclooxygenase-2 (IC50 values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo. Orally active.
| Molecular Weight | 411.3 |
| Formula | C17H12BrFO2S2 |
| CAS Number | 88149-94-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 41.13 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Garrido, et al. Bioorg Med Chem Lett. Synthesis and activity of small molecule GPR40 agonists.
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