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DTNB

Cat. No. M11509

All AbMole products are for research use only, cannot be used for human consumption.

DTNB Structure
Synonym:

Ellman’s Reagent; 5,5′-Dithiobis(2-nitrobenzoic acid)

Size Price Availability Quantity
500mg USD 30  USD30 In stock
1g USD 40  USD40 In stock
5g USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

DTNB (Ellman's Reagent) is a chemical used for quantifying the amount or concentration of sulfhydryl groups. It is often used to detect free sulfhydryl groups. DTNB is also an allosteric inhibitor of dengue virus protease (NS2B-NS3Pro) and Streptomyces protease.

Chemical Information
Molecular Weight 396.35
Formula C14H8N2O8S2
CAS Number 69-78-3
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hvard Foyn, et al. Methods Mol Biol. DTNB-Based Quantification of In Vitro Enzymatic N-Terminal Acetyltransferase Activity

[2] Chi-Chang Lin, et al. Biosens Bioelectron. AuNPs@mesoSiO2 composites for SERS detection of DTNB molecule

[3] Joshua B Owen, et al. Methods Mol Biol. Measurement of oxidized/reduced glutathione ratio

[4] M R Toon, et al. Biochim Biophys Acta. Binding of DTNB to band 3 in the human red cell membrane

[5] T Nagaoka, et al. J Biochem. DTNB modification of SH groups of isocitrate dehydrogenase from Bacillus stearothermophilus purified by affinity chromatography

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Keywords: DTNB, Ellman’s Reagent; 5,5′-Dithiobis(2-nitrobenzoic acid) supplier, inhibitors, activators

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