Free shipping on all orders over $ 500

dTAGV-1 TFA 

Cat. No. M29737

All AbMole products are for research use only, cannot be used for human consumption.

dTAGV-1 TFA  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

dTAGV-1 TFA is a potent and selective degrader of mutant FKBP12F36V fusion proteins. dTAGV-1 TFA can induce degradation of FKBP12F36V-Nluc in vivo.

Chemical Information
Molecular Weight 1361.56
Formula C70H91F3N6O16S
CAS Number 2624313-15-9
Form Solid
Solubility (25°C) DMSO 37.5 mg/mL (ultrasonic)
Storage -20°C, protect from light, dry, sealed
References

[1] Mandeep Sekhon, et al. BMC Health Serv Res. Development of a theory-informed questionnaire to assess the acceptability of healthcare interventions

[2] Susana P Alves, et al. Lipids. Trans-10 18:1 in ruminant meats: A review

[3] Jérôme Clerc. Q J Nucl Med Mol Imaging. Radioiodine therapy of thyroid autonomy

[4] Ammar Rashid, et al. J Pak Med Assoc. Trans-Fatty Acid (TFA) elimination in Pakistan: A situational analysis

[5] Chaoyang Li, et al. Prev Chronic Dis. Global Surveillance of trans-Fatty Acids

Related PROTAC Products
GDC-2992

GDC-2992 is an orally active androgen receptor (AR) degrader. GDC-2992 degrads AR with a DC50 value of 2.7 nM and inhibits proliferation with an IC50 valude of 9.7 nM in VCaPcells.

Setidegrasib

Setidegrasib is a PROTAC KRAS degrader (DC50: 37 nM). Setidegrasib induces the degradation of G12D-mutation KRAS protein. Setidegrasib has antitumor effect.

PROTAC HK2 Degrader-1

PROTAC HK2 Degrader-1 is a PROTAC consisting of Lonidamine as a target protein Hexokinase 2 (HK2) inhibitor and Thalidomide as a CRBN ligand-linked PROTAC. PROTAC HK2 Degrader-1 selectively inhibits the proliferation of breast cancer cells by forming a ternary complex through the ubiquitin-proteasome system to degrade Hexokinase 2 (HK2) protein leading to mitochondrial damage and cell death.

ZXH-4-130 TFA

ZXH-4-130 TFA is a highly potent and selective degrader of CRBN. ZXH-4-130 is a CRBN-VHL compound (hetero-PROTAC).

MS4322

MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5.

  Catalog
Abmole Inhibitor Catalog




Keywords: dTAGV-1 TFA  supplier, PROTAC, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.