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DS-3801b

Cat. No. M21062

All AbMole products are for research use only, cannot be used for human consumption.

DS-3801b Structure

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Quality Control & Documentation
Biological Activity

DS-3801b is a non-mescaline GPR38 agonist, DS-3801b is expected to be a novel gastrointestinal prokinetic agent for the study of functional gastrointestinal disorders such as gastroparesis and chronic constipation.

Chemical Information
Molecular Weight 465.63
Formula C28H39N3O3
CAS Number 1369412-66-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Narihiro Toda, et al. Bioorg Med Chem Lett. Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure

[2] Jo Ishizawa, et al. Cancer Res. Predictive Gene Signatures Determine Tumor Sensitivity to MDM2 Inhibition

[3] Justin Dennie, et al. J Clin Pharmacol. A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of DS-3801b, a Motilin Receptor Agonist, in Healthy Subjects

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