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DS-1205b free base 

Cat. No. M28955

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DS-1205b free base  Structure
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Biological Activity

DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.

Chemical Information
Molecular Weight 735.8
Formula C41H42FN5O7
CAS Number 1855860-24-0
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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  Catalog
Abmole Inhibitor Catalog




Keywords: DS-1205b free base  supplier, TAM Receptor, inhibitors, activators

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