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Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.
| Molecular Weight | 388.46 |
| Formula | C17H22N2O.C4H6O4 |
| CAS Number | 562-10-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Okşan Derinz-Gleryz. Doxylamine succinate overdose: Slurred speech and visual hallucination
[4] Dennis J Cada, et al. Doxylamine succinate/pyridoxine hydrochloride
[5] J A Skare, et al. Safety assessment of OTC drugs: doxylamine succinate
| Related Histamine Receptor Products |
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| Dimethindene
Dimethindene is a potent, selective histamine H1 antagonist. |
| ABT-288
ABT-288 is a competitive, potent and selective histamine H3 receptor (H3R) antagonist. |
| A-349821
A-349821 is a histamine H3 receptor antagonist characterized as a radioligand ([3H]-A-349821) for in vivo receptor occupancy assessment. |
| Betazole
Betazole (Ametazole), a pyrazole analogue of histamine, is an orally active histamine H2 receptor agonist. |
| Tiotidine
Tiotidine (ICI 125211) is a potent and selective antagonist of histamine H2-receptor (pA2=7.3-7.8 for guinea-pig right atrium). |
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