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Doripenem is the most active carbapenem (MIC90, 1 to 4 mg/mL) against penicillin-resistant streptococci. Doripenem demonstrates in vitro activity similar to that of meropenem against gram-negative pathogens and to that of imipenem against gram-positive pathogens.
| Molecular Weight | 438.52 |
| Formula | C15H24N4O6S2.H2O |
| CAS Number | 364622-82-2 |
| Form | Solid |
| Solubility (25°C) | DMSO 36 mg/mL Water 26 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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