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Dofetilide

Cat. No. M8034

All AbMole products are for research use only, cannot be used for human consumption.

Dofetilide Structure
Synonym:

UK 68789

Size Price Availability Quantity
5mg USD 65  USD65 In stock
10mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Dofetilide is a Class III antiarrhythmic and hERG channel blocker. Dofetilide selectively blocks the rapid component of the delayed rectifier outward potassium current (IKr).

Chemical Information
Molecular Weight 441.56
Formula C19H27N3O5S2
CAS Number 115256-11-6
Solubility (25°C) DMSO: ≥20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ilaria Marcantoni, et al. Dofetilide-Induced Microvolt T-Wave Alternans

[2] Deborah L Wolbrette, et al. A Quarter of a Century Later: What is Dofetilide's Clinical Role Today?

[3] JoEllyn C Moore, et al. Dofetilide for suppression of atrial fibrillation in hypertrophic cardiomyopathy: A case series and literature review

[4] Fatemah Shenasa, et al. Dofetilide: Electrophysiologic Effect, Efficacy, and Safety in Patients with Cardiac Arrhythmias

[5] J P Mounsey, et al. Cardiovascular drugs. Dofetilide

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Keywords: Dofetilide, UK 68789 supplier, inhibitors, activators

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