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DN401

Cat. No. M31376

All AbMole products are for research use only, cannot be used for human consumption.

DN401 Structure

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Quality Control & Documentation
Biological Activity

DN401 is a potent TRAP1 and Hsp90 inhibitor with anticancer activity with IC50 values of 79 nM and 698 nM, respectively.

Chemical Information
Molecular Weight 309.36
Formula C18H19N3O2
CAS Number 2135749-60-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hye-Kyung Park, et al. Exp Mol Med. Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1

[2] Hye-Kyung Park, et al. J Med Chem. Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors

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Hsp70-derived octapeptide

Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs.

  Catalog
Abmole Inhibitor Catalog




Keywords: DN401 supplier, HSP, inhibitors, activators

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