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Distamycin A

Cat. No. M22494

All AbMole products are for research use only, cannot be used for human consumption.

Distamycin A Structure
Synonym:

Stallimycin; NSC-82150

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Quality Control & Documentation
Biological Activity

Distamycin A (Stallimycin, NSC-82150), an oligopeptide antibiotic, is a minor groove binder which binds to B-form DNA, preferentially at A/T rich sites.Distamycin A can change Enediyne-induced DNA cleavage sites and enhances apoptosis.

Chemical Information
Molecular Weight 481.51
Formula C22H27N9O4
CAS Number 636-47-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pier Giovanni Baraldi, et al. Bioorg Med Chem. Hybrid molecules between distamycin A and active moieties of antitumor agents

[2] Pier Giovanni Baraldi, et al. Curr Top Med Chem. Distamycin A as stem of DNA minor groove alkylating agents

[3] P Cozzi, et al. Curr Pharm Des. Cytotoxics derived from distamycin A and congeners

[4] M Durand, et al. Biochemistry. Distamycin A complexation with a nucleic acid triple helix

[5] J C Stockert, et al. Histochemistry. DNA-induced distamycin A fluorescence

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Keywords: Distamycin A, Stallimycin; NSC-82150 supplier, Antibiotic, inhibitors, activators

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