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Distamycin A (Stallimycin, NSC-82150), an oligopeptide antibiotic, is a minor groove binder which binds to B-form DNA, preferentially at A/T rich sites.Distamycin A can change Enediyne-induced DNA cleavage sites and enhances apoptosis.
| Molecular Weight | 481.51 |
| Formula | C22H27N9O4 |
| CAS Number | 636-47-5 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] P Cozzi, et al. Curr Pharm Des. Cytotoxics derived from distamycin A and congeners
[4] M Durand, et al. Biochemistry. Distamycin A complexation with a nucleic acid triple helix
[5] J C Stockert, et al. Histochemistry. DNA-induced distamycin A fluorescence
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