All AbMole products are for research use only, cannot be used for human consumption.
Disitertide (P144) diammonium is a polypeptide inhibitor of transforming growth factor TGFβ1, specifically blocking its interaction with the receptor. Disitertide diammonium was also an inhibitor of PI3K and an inducer of apoptosis.
Pathol Oncol Res. 2021 Apr 29;27:1609761.
MiR-543 Inhibits the Migration and Epithelial-To-Mesenchymal Transition of TGF-β-Treated Endometrial Stromal Cells via the MAPK and Wnt/β-Catenin Signaling Pathways
Disitertide diammonium purchased from AbMole
| Molecular Weight | 1614.88 |
| Formula | C68H115N19O22S2 |
| CAS Number | 272105-42-7 (free base) |
| Solubility (25°C) | DMSO 10 mg/mL Water 5 mg/mL (ultrasonic and adjust pH with NH3·H2O) |
| Storage | -20°C, protect from light, dry, sealed |
| Related TGF-beta/Smad Products |
|---|
| A 83-01 sodium
A 83-01 sodium is a potent inhibitor of TGF-β type I receptors ALK5, ALK4, and ALK7, inhibiting ALK5, ALK4, and ALK7-induced transcription with IC50 values of 12 nM, 45 nM, and 7.5 nM, respectively. |
| Myristoyl tetrapeptide-12
Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. |
| H-Leu-Ser-Lys-Leu-OH
H-Leu-Ser-Lys-Leu-OH (LSYL) is a latency-associated peptide at the amino terminus of LAP, with inhibitory effect on TGF-β1 activation. |
| SY-LB-35
SY-LB-35 is a potent bone morphogenetic protein (BMP) receptor agonist. |
| DT-6
DT-6 is an effective TGF-β1 inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
