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Diphenidol 

Cat. No. M30981

All AbMole products are for research use only, cannot be used for human consumption.

Diphenidol  Structure

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Quality Control & Documentation
Biological Activity

Diphenidol is an orally active antiemetic. Diphenidol reduces abnormal neuropathic pain and TNF-α overexpression in rats following chronic compression injury. Diphenidol also has local anaesthetic activity and inhibits sodium currents. Diphenidol can be used in studies of meniere′s disease, anti-vertigo, antiemetic and analgesia.

Chemical Information
Molecular Weight 309.45
Formula C21H27NO
CAS Number 972-02-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Liu Yang, et al. Fa Yi Xue Za Zhi. Forensic Analysis of 9 Poisoning Death Cases Caused by Oral Administration of Diphenidol

[2] Liu Yang, et al. Drug Test Anal. Identifying metabolites of diphenidol by liquid chromatography-quadrupole/orbitrap mass spectrometry using rat liver microsomes, human blood, and urine samples

[3] Yu-Wen Chen, et al. Neurosci Lett. Systemic diphenidol reduces neuropathic allodynia and TNF-alpha overexpression in rats after chronic constriction injury

[4] Yuk-Man Leung, et al. Neuropharmacology. Diphenidol inhibited sodium currents and produced spinal anesthesia

[5] A J Wasserman, et al. Chest. Diphenidol treatment of arrhythmias

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Keywords: Diphenidol  supplier, inhibitors, activators

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