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DiMNF is a naphthoflavone derivative, selective aryl hydrocarbon receptor modulator (SAhRM). DiMNF is an AHR ligand that does not induce the expression of AHR dependent genes, such as CYP1A1, but inhibits the expression of cytokine-induced acute phase response proteins such as serum amyloid A and complement C3.
| Molecular Weight | 332.35 |
| Formula | C21H16O4 |
| CAS Number | 14756-24-2 |
| Solubility (25°C) | DMSO: ≥13 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Sbastien Besteiro. The role of host autophagy machinery in controlling Toxoplasma infection
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