All AbMole products are for research use only, cannot be used for human consumption.
Dihydrotestosterone is a hormone with powerful androgenic actions, causes the body to mature during puberty and is responsible for many of the physical characteristics associated with adult males. It can be used to construct animal models of polycystic ovary syndrome (PCOS).
Am J Pathol. 2024 Sep 05;S0002-9440(24)00331-6.
Testosterone-induced H3K27 deacetylation participates in granulosa cell proliferation suppression and pathogenesis of Polycystic Ovary Syndrome
Dihydrotestosterone purchased from AbMole
Mol Cell Endocrinol. 2024 Sep 26.
TIGAR relieves PCOS by inhibiting granulosa cell apoptosis and oxidative stress through activating Nrf2
Dihydrotestosterone purchased from AbMole
BMC Women's Health. 2024 Jan;25.
PHLPP1 inhibits the growth and aerobic glycolysis activity of human ovarian granular cells through inactivating AKT pathway
Dihydrotestosterone purchased from AbMole
Drug Chem Toxicol. 2016 Oct;39(4):392-9.
Effects of 2,4-dichlorophenoxyacetic acid on the ventral prostate of rats during the peri-pubertal, pubertal and adult stage
Dihydrotestosterone purchased from AbMole
J Steroid Biochem Mol Biol. 2013 Nov;138:54-62.
Effect of androgens on different breast cancer cells co-cultured with or without breast adipose fibroblasts
Dihydrotestosterone purchased from AbMole
| Cell Experiment | |
|---|---|
| Cell lines | Primary pig hepatocytes |
| Preparation method | In steroid metabolism studies, hepatocytes were incubated in 10 ml of basal growth medium containing phenol red-free DMEM with 10% of charcoal treated FBS fortified with 10 µM (final concentration) of androstenone, 17β-estradiol or dihydrotestosterone. |
| Concentrations | 10 µM |
| Incubation time | 48 h |
| Animal Experiment | |
|---|---|
| Animal models | SOD1-G93A mutant mice with the congenic C57BL/6J background |
| Formulation | Saline |
| Dosages | 5 mg |
| Administration | silastic implant |
| Molecular Weight | 290.44 |
| Formula | C19H30O2 |
| CAS Number | 521-18-6 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Androgen Receptor Products |
|---|
| LGD-3303
LGD-3303 is a nonsteroidal, nonaromatizable selective androgen receptor ligand that binds to the androgen receptor with high affinity in a radiolabeled to competitive binding assay (Ki=0.9 nM). |
| Ar-V7-IN-1
Ar-V7-IN-1 is a potent inhibitor of Ar-V7. AR-V7 is a hormone-independent splice variant of the androgen receptor. Ar-V7-IN-1 has the potential for the research of various indications such as prostate cancer. |
| SC912
SC912 is a potent and selective AR-V7 inhibitor with IC50 of 0.36 μM. SC912 binds directly to AR-FL and AR-V7 proteins, inhibites nuclear localization and chromatin binding capabilities. SC912 exerts anticancer activity through inhibition of proliferation, induction of cell cycle arrest and apoptosis. |
| A4B17
A4B17 is an androgen receptor N-terminal inhibitor, which can be used for the research of androgen-responsive prostate cancer. |
| AZ'3137
AZ‘3137 is an orally active PROTAC-type androgen receptor (AR) degrader, with a DC50 value of 22 nM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
