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Dihydrokainic acid

Cat. No. M7744

All AbMole products are for research use only, cannot be used for human consumption.

Dihydrokainic acid Structure
Size Price Availability Quantity
1mg USD 140  USD140 In stock
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Quality Control & Documentation
Biological Activity

Dihydrokainic acid is a selective inhibitor of the GLT-1 glutamate transporter. At higher concentrations, dihydrokainate is a weak inhibitor of AMPA/kainate glutamic acid receptors.

Chemical Information
Molecular Weight 215.25
Formula C10H17NO4
CAS Number 52497-36-6
Form Solid
Solubility (25°C) Water: ≥10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shao-Wen Tian, et al. Glutamate transporter GLT1 inhibitor dihydrokainic acid impairs novel object recognition memory performance in mice

[2] Mikko Gynther, et al. Blood-brain barrier permeability and brain uptake mechanism of kainic acid and dihydrokainic acid

[3] A Lehmann, et al. Dihydrokainic acid affects extracellular taurine and phosphoethanolamine levels in the hippocampus

[4] S P Butcher, et al. On the epileptogenic effects of kainic acid and dihydrokainic acid in the dentate gyrus of the rat

[5] M D Muoz, et al. Effects of dihydrokainic acid on extracellular amino acids and neuronal excitability in the in vivo rat hippocampus

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Keywords: Dihydrokainic acid supplier, GLUT, inhibitors, activators

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