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Dexrazoxane (ICRF-187, ADR-529, DXZ) is an iron chelator that can be used to prevent DOX-induced cardiotoxicity.
| Molecular Weight | 268.27 |
| Formula | C11H16N4O4 |
| CAS Number | 24584-09-6 |
| Solubility (25°C) | DMSO: ≥20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Long Li, et al. Dexrazoxane ameliorates radiation-induced heart disease in a rat model
[2] Chiamaka Eneh, et al. Dexrazoxane
[3] Anchit Bhagat, et al. Anthracycline-Induced Cardiotoxicity: Causes, Mechanisms, and Prevention
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