Free shipping on all orders over $ 500
Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine is an inhibitor of autophagy and Toll-like receptors (TLRs). Desethyl Chloroquine diphosphate has anti-plasmodium activity.
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Molecular Weight | 389.82 |
| Formula | C16H25ClN3O4P |
| CAS Number | 247912-76-1 |
| Purity | >99% |
| Solubility | Water ≥ 10 mg/mL |
| Storage | 4°C , protect from light , dry , sealed |
| Related Products |
|---|
| RP-6306
RP-6306 is the only inhibitor of PKMYT1 currently available in the clinic, which is synthetically fatal to CCNE1 amplification, FBXW7 deletion or other specific mutations. |
| Myxothiazol
Myxothiazol, an antifungal antibiotic, is an inhibitor of mitochondrial electron transport chain complex III (Complex III or Bc1 complex). |
| WGA
Wheat agglutinin (WGA) is isolated from wheat (Triticum vulgaris, Weat germ), WGA selectively binds to glycoproteins and glycolipids of n-acetylglucosamine (GlcNAc) and n-acetylneuraminine (sialic acid) residues. |
| Antide
Sequence：Ac-D2Nal-DCpa-DPal-Ser-Lys(nicotinoyl)-DLys(nicotinoyl)-Leu-Lys(isopropyl)-Pro-DAla-NH2 |
| NE-CARBOXYMETHYL-L-LYSINE
NE-CARBOXYMETHYL-L-LYSINE |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
