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Demeclocycline

Cat. No. M40716

All AbMole products are for research use only, cannot be used for human consumption.

Demeclocycline Structure

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Quality Control & Documentation
Biological Activity

Demeclocycline is an orally active semisynthetic tetracycline antibiotic that affects protein synthesis by binding to the 30S ribosomal subunit, thereby inhibiting the binding of aminoacyl tRNA. It has broad-spectrum antibacterial activity.

Chemical Information
Molecular Weight 464.85
Formula C21H21ClN2O8
CAS Number 127-33-3
Solubility (25°C) Water 1.5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kota Iwahori et al. Sci Rep. A randomized phase 2 study on demeclocycline in patients with mild-to-moderate COVID-19

[2] Susobhan Sarkar et al. Front Immunol. Demeclocycline Reduces the Growth of Human Brain Tumor-Initiating Cells: Direct Activity and Through Monocytes

[3] J Miell et al. Int J Clin Pract. Evidence for the use of demeclocycline in the treatment of hyponatraemia secondary to SIADH: a systematic review

[4] A Hayek et al. JAMA. Demeclocycline-induced diabetes insipidus

[5] J R Oster et al. Lancet. Demeclocycline-induced renal failure

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Keywords: Demeclocycline supplier, Antibiotic, inhibitors, activators

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