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DDR2-IN-1

Cat. No. M58475

All AbMole products are for research use only, cannot be used for human consumption.

DDR2-IN-1 Structure

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Quality Control & Documentation
Biological Activity

DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1 can be used for osteoarthritis research.

Chemical Information
Molecular Weight 526.03
Formula C27H32ClN5O4
CAS Number 1573053-23-2
Form Solid
Solubility (25°C) DMSO 120 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related Discoidin Domain Receptor Products
DDR1-IN-1 dihydrochloride 

DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM).

DDR1/2 inhibitor-2

DDR1/2 inhibitor-2 is a DDR1/DDR2 inhibitor, with IC50 values less than 100 nM.

WRG-28 

WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC50 of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of mice.

DDR Inhibitor 

DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM.

BAY-826 

BAY-826 is a selective and potent TIE-2 inhibitor with a Kd of 1.6 nM, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: DDR2-IN-1 supplier, Discoidin Domain Receptor, inhibitors, activators

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