DDR2-IN-1 - Search Results | AbMole BioScience

About 5 results found for searched term "DDR2-IN-1" (0.123 seconds)

Cat.No.	Name	Target
M10520	FGFR1/DDR2 inhibitor 1	Others
	ABM-497585
	FGFR1/DDR2 inhibitor 1 is an orally active inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM and 3.2 nM, respectively.
M58475	DDR2-IN-1	Discoidin Domain Receptor
	DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1 can be used for osteoarthritis research.
M9626	Sitravatinib	VEGFR/PDGFR
	MGCD516; MG516
	Sitravatinib (MGCD516) is an orally active receptor tyrosine kinase (RTK) inhibitor. Inhibition of Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, and TRKB at 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, respectively. 29 nM, 5 nM and 9 nM. Sitravatinib alone has a potent antitumor effect and enhances pD-1 blockade activity by promoting the antitumor immune microenvironment.
M28770	DDR Inhibitor	Discoidin Domain Receptor
	DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM.
M43492	DDR1/2 inhibitor-2	Discoidin Domain Receptor
	DDR1/2 inhibitor-2 is a DDR1/DDR2 inhibitor, with IC50 values less than 100 nM.