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DCH36_06 

Cat. No. M30335

All AbMole products are for research use only, cannot be used for human consumption.

DCH36_06  Structure

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Quality Control & Documentation
Biological Activity

DCH36_06 is a potent and selective p300/CBP inhibitor with IC50s of 0.6 μM and 3.2 μM for p300 and CBP, respectively. DCH36_06 mediated p300/CBP inhibition leading to hypoacetylation on H3K18 in leukemic cells. Anti-tumor activity.

Chemical Information
Molecular Weight 372.83
Formula C18H13ClN2O3S
CAS Number 593273-05-3
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage 4°C, protect from light
References

[1] Wenchao Lu, et al. Bioorg Med Chem. Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors

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  Catalog
Abmole Inhibitor Catalog




Keywords: DCH36_06  supplier, Histone Acetyltransferase, inhibitors, activators

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