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Daptomycin (Cubicin) is a novel lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms. Daptomycin is active against Gram-positive bacteria only. It has proven in vitro activity against enterococci (including glycopeptide-resistant Enterococci (GRE)), staphylococci (including methicillin-resistant Staphylococcus aureus), streptococci and corynebacteria. Daptomycin disrupts plasma membrane function, which makes it useful against resistant bacteria. It is thought to cause rapid depolarization thereby inhibiting protein, DNA and RNA synthesis. Daptomycin and nafcillin in combination significantly improved antibacterial activity against VISA.
| Molecular Weight | 1620.67 |
| Formula | C72H101N17O26 |
| CAS Number | 103060-53-3 |
| Solubility (25°C) | Water 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Antibiotic Products |
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| Rosoxacin
Rosoxacin (Acrosoxacin) is an orally active and broad-spectrum antibacterial quinolone antibiotic. Rosoxacin inhibits Gram-negative bacteria, including N. gonorrhoeae (MIC range=0.03-0.125 µg/mL). |
| 2-Nitrosopyridine
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| Cethromycin
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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