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D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator. In microbiology: Mannitol is a good medium for certain microorganisms. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells. Mannitol can also be used as a facilitating agent for the transportation of pharmaceuticals directly into the brain. The arteries of the blood-brain barrier are much more selective than normal arteries. D-Mannitol is commonly used in the circuit prime of a heart lung machine during cardiopulmonary bypass.
Molecular Weight | 182.17 |
Formula | C6H14O6 |
CAS Number | 69-65-8 |
Solubility (25°C) | Water ≥ 60 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Chengrong Cao, et al. J Chem Phys. Liquid-liquid transition kinetics in D-mannitol
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