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Cyclocreatine acts as a brain-penetrant and potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine suppresses creatine metabolism ameliorating the cognitive, autistic and epileptic phenotype in a mouse model of creatine transporter defciency. Cyclocreatine decreases plaque-adjacent neuronal dystrophy in TREM2-deficient mice with amyloid-β pathology. Cyclocreatine is proming for research of ischemic heart disease, cardiovascular diseases, Alzheimer’s disease and other neurodegenerative diseases associated with microglial dysfunction, prostate cancer.
| Molecular Weight | 143.15 |
| Formula | C5H9N3O2 |
| CAS Number | 35404-50-3 |
| Form | Solid |
| Solubility (25°C) | 1M HCl: ≥ 30 mg/mL |
| Storage | 4°C, protect from light |
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