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Cyasterone

Cat. No. M4749

All AbMole products are for research use only, cannot be used for human consumption.

Cyasterone Structure
Size Price Availability Quantity
1mg USD 30  USD30 In stock
5mg USD 77  USD77 In stock
10mg USD 135  USD135 In stock
20mg USD 220  USD220 In stock
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Quality Control & Documentation
Biological Activity

Cyasterone, a natural EGFR inhibitor, was primarily isolated from Ajuga Decumbens Thunb (Labiatae). Cyasterone showed antiproliferative effects by inducing apoptosis and cell cycle arrest. Cyasterone could be used in studies against human tumors.

Chemical Information
Molecular Weight 520.65
Formula C29H44O8
CAS Number 17086-76-9
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Junlang Zhu, et al. Cyasterone accelerates fracture healing by promoting MSCs migration and osteogenesis

[2] XinGang Lu, et al. Anti-proliferation effects, efficacy of cyasterone in vitro and in vivo and its mechanism

[3] Fuqiang Li, et al. A simple LC-MS method for determination of cyasterone in rat plasma: application to a pilot pharmacokinetic study

[4] Yui Hirayama, et al. Stereochemical assignment of C-24 and C-25 of amarasterone A, a putative biosynthetic intermediate of cyasterone

[5] Keiko Okuzumi, et al. Structure elucidation of cyasterone stereoisomers isolated from Cyathula officinalis

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Keywords: Cyasterone supplier, EGFR/HER2, inhibitors, activators

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