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Cyanidin chloride is a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties, could be used for treatment of diabetes mellitus complications. Cyanidin Chloride (IdB 1027) inhibits receptor activator of NF-κB ligand (RANKL)-induced NF-κB activation, suppresses the degradation of IκB-α and attenuates the phosphorylation of extracellular signal-regulated kinases (ERK). Cyanidin Chloride (IdB 1027) abrogates RANKL-induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1), and the expression of c-Fos. Cyanidin Chloride (IdB 1027) protects against OVX-induced bone loss in OVX-induced osteoporosis mouse model.
Molecular Weight | 322.7 |
Formula | C15H11ClO6 |
CAS Number | 528-58-5 |
Form | Solid |
Solubility (25°C) | DMSO 20 mg/mL |
Storage | -20°C, sealed |
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