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Cyamemazine

Cat. No. M8292

All AbMole products are for research use only, cannot be used for human consumption.

Cyamemazine Structure

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Biological Activity

Cyamemazine is a potent antagonist of 5-HT2C and 5-HT3 receptors with antipsychotic and anxiolytic properties.

Chemical Information
Molecular Weight 323.46
Formula C19H21N3S
CAS Number 3546-03-0
Solubility (25°C) DMSO: ≥5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Charles Khouri, et al. Cyamemazine (Tercian ®): Exploration of extrapyramidal syndrome cases contained in the French pharmacovigilance database

[2] Amine Benyamina, et al. Potential role of cortical 5-HT(2A) receptors in the anxiolytic action of cyamemazine in benzodiazepine withdrawal

[3] William Crumb, et al. Cyamemazine metabolites: effects on human cardiac ion channels in-vitro and on the QTc interval in guinea pigs

[4] M Bourin, et al. Cyamemazine as an anxiolytic drug on the elevated plus maze and light/dark paradigm in mice

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