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CP-471474

Cat. No. M8056

All AbMole products are for research use only, cannot be used for human consumption.

CP-471474 Structure

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Quality Control & Documentation
Biological Activity

CP-471474 is a broad spectrum inhibitor of matrix metalloproteinases. CP-471474 has a low nM IC50 efficacy for MMP-2, MMP-3, MMP-9, and MMP-13. CP-471474 has low potency against MMP-1 (IC50 > 1 uM). CP-471474 prevents left ventricular remodeling after experimental myocardial infarction in mice. CP-471474 also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models.

Chemical Information
Molecular Weight 368.38
Formula C16H17FN2O5S
CAS Number 210755-45-6
Solubility (25°C) DMSO: ≥20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yan Wei, et al. Nanoliter Quantitative High-Throughput Screening with Large-Scale Tunable Gradients Based on a Microfluidic Droplet Robot under Unilateral Dispersion Mode

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  Catalog
Abmole Inhibitor Catalog




Keywords: CP-471474 supplier, inhibitors, activators

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