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CP-101606 mesylate (Traxoprodil mesylate) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. CP-101606 mesylate has been shown to be neuroprotective in animal models of brain injury and stroke.
| Molecular Weight | 423.52 |
| Formula | C20H25NO3 · CH4O3S |
| CAS Number | 188591-67-5 |
| Solubility (25°C) | DMSO: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Ana Paula Naspolini, et al. Traxoprodil decreases pentylenetetrazol-induced seizures
[3] Kathleen R Gogas. Glutamate-based therapeutic approaches: NR2B receptor antagonists
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