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CP-10 is a PROTAC connected by ligands for Cereblon and CDK, with highly selective, specific, and remarkable CDK6 degradation (DC50=2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6.
| Molecular Weight | 871.94 |
| CAS Number | 2366268-80-4 |
| Solubility (25°C) | DMSO 150 mg/mL |
| Storage | -20°C, sealed |
[1] No authors listed. Pyrantel
[4] C J Cornish, et al. S100 protein CP-10 stimulates myeloid cell chemotaxis without activation
[5] S E Iismaa, et al. Recombinant and cellular expression of the murine chemotactic protein, CP-10
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