Free shipping on all orders over $ 500

Coumermycin A1 

Cat. No. M30102

All AbMole products are for research use only, cannot be used for human consumption.

Coumermycin A1  Structure
Size Price Availability
1mg USD 450  USD450 4-7 Days
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1 shows anti-orthopoxvirus activity.

Chemical Information
Molecular Weight 1110.08
Formula C55H59N5O20
CAS Number 4434-05-3
Form Solid
Solubility (25°C) DMSO 50 mg/mL (Need ultrasonic and warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Arnaud Vanden Broeck, et al. J Med Chem. Structural Basis for DNA Gyrase Interaction with Coumermycin A1

[2] H L Newmark, et al. J Pharm Sci. Coumermycin A1-Biopharmaceutical studies. II

[3] J Fedorko, et al. Appl Microbiol. In vitro activity of coumermycin A1

[4] C M Perronne, et al. Antimicrob Agents Chemother. Treatment of Staphylococcus aureus endocarditis in rats with coumermycin A1 and ciprofloxacin, alone or in combination

[5] M J Ryan. Biochemistry. Coumermycin A1: A preferential inhibitor of replicative DNA synthesis in Escherichia coli. I. In vivo characterization

Related JAK Products
iJak-381 

iJak-381 is a JAK1/2 inhibitor with anti-inflammatory activity.

Ritlecitinib (malonate)

Ritlecitinib (PF-06651600) malonate is an orally active and selective JAK3 inhibitor with an IC50 of 33.1 nM.

Deuruxolitinib

Deuruxolitinib is a deuterated Ruxolitinib (INCB18424), which modulates the activity of JAK1/JAK2. Deuruxolitinib can be used for the research of hair loss disorders.

A-005

A-005 is a potentially first-in-class, brain-penetrating TYK2 allosteric inhibitor for studies related to neuroinflammatory and neurodegenerative diseases.

Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)

Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide corresponding to amino acids 475 to 491 of mouse JAK2.

  Catalog
Abmole Inhibitor Catalog




Keywords: Coumermycin A1  supplier, JAK, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.