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Corylin is an orally active flavonoid anti-inflammatory and osteogenic agent that inhibits IL-6-induced STAT3 promoter activity and STAT3 phosphorylation. Corylin is a major bioactive compound isolated from Psoralea corylifolia L; antibiotic or anticancer compound. Corylin showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 1.37 uM. Corylin induced adipocyte browning and lipolysis through SIRT1 or β3-AR-dependent pathways.
| Molecular Weight | 320.34 |
| Formula | C20H16O4 |
| CAS Number | 53947-92-5 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage | 2-8°C, protect from light |
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