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Concizumab

Cat. No. M24605

All AbMole products are for research use only, cannot be used for human consumption.

Concizumab Structure
Synonym:

NN 7415; mAb 2021 Anti-TFPI Recombinant Antibody

Size Price Availability
1mg USD 350  USD350 4-7 Days
5mg USD 900  USD900 4-7 Days
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Quality Control & Documentation
Biological Activity

Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that binds to the Kunitz-type protease inhibitor (KPI) 2 structural domain of TFPI, thereby blocking the interaction of this structural domain with the FXa active site. Concizumab can be used in the study of haemophilia.

Chemical Information
CAS Number 1312299-39-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Susan J Keam. Drugs. Concizumab: First Approval

[2] Samantha Pasca. J Blood Med. Concizumab as a Subcutaneous Prophylactic Treatment Option for Patients with Hemophilia A or B: A Review of the Evidence and Patient's Perspectives

[3] Amy D Shapiro, et al. Blood Adv. Long-term efficacy and safety of subcutaneous concizumab prophylaxis in hemophilia A and hemophilia A/B with inhibitors

[4] Amy D Shapiro. Blood Adv. Concizumab: a novel anti-TFPI therapeutic for hemophilia

[5] Amy D Shapiro, et al. Blood. Subcutaneous concizumab prophylaxis in hemophilia A and hemophilia A/B with inhibitors: phase 2 trial results

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Keywords: Concizumab, NN 7415; mAb 2021 Anti-TFPI Recombinant Antibody supplier, inhibitors, activators

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