Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells.
| Molecular Weight | 354.4 |
| Formula | C21H22O5 |
| CAS Number | 14348-21-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL (ultrasonic) |
| Storage | 4°C, protect from light, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Others Products |
|---|
| Lutonarin
Lutonarin is a antioxidant agent that can be isolated from green barley leaves. Lutonarin (Isoorientin 7-O-glucoside) is a natural product found in aerial part of Silene jeniseensis. |
| Ethyl glucoside
Ethyl glucoside is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS. |
| Methyl 2,4-dihydroxyphenylacetate
Methyl 2,4-dihydroxyphenylacetate is a natural product isolated from Nigella damascena seeds with selective phytotoxic effects. |
| Magnesium Lithospermate B
Magnesium Lithospermate B is a derivative of caffeic acid tetramer extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroinflammation and attenuates neurodegeneration. |
| 5-O-Methylvisamminol
5-O-Methylvisamminol, a (furo) chromone identified in the extract of T. glauca. 5-O-Methylvisamminol is useful in (chemical) phylogeny and is a possible excellent chemotaxonomic marker for Apiaceae. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
