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CMPD101

Cat. No. M6617

All AbMole products are for research use only, cannot be used for human consumption.

CMPD101 Structure

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Quality Control & Documentation
Biological Activity

CMPD101 is a potent and selective GRK2/3 inhibitor (IC50 values are 32 and 54 nM for GRK3 and GRK2, respectively). Exhibits selectivity for GRK2/3 over GRK1/5. Reduces DAMGO-induced desensitization and internalization of μ-opioid receptors.

Chemical Information
Molecular Weight 466.46
Formula C24H21F3N6O
CAS Number 865608-11-3
Solubility (25°C) DMSO 46.65 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kemp, et al. Am J Respir Cell Mol Biol. Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells.

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Keywords: CMPD101 supplier, inhibitors, activators

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