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Closantel is gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
| Molecular Weight | 663.07 |
| Formula | C22H14Cl2I2N2O2 |
| CAS Number | 57808-65-8 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Vanessa Luciano, et al. Closantel is an allosteric inhibitor of human Taspase1
[2] Basma Saleh, et al. Analytical Separation of Closantel Enantiomers by HPLC
[3] Sepideh Ghods, et al. Closantel Retinal Toxicity: Case Report and Literature Review
[4] No authors listed. Vet Rec. Closantel toxicity causing blindness and death in hoggs
[5] M Michiels, et al. The metabolism and fate of closantel (Flukiver) in sheep and cattle
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