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Clofibride

Cat. No. M29761

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Clofibride Structure

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Quality Control & Documentation
Biological Activity

Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and marked hypocholesterolaemic and hypotriglyceridaemic activity. Clofibride is converted into 4-chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) in vivo.

Chemical Information
Molecular Weight 327.8
Formula C16H22ClNO4
CAS Number 26717-47-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] N S Magalhaes, et al. J Microencapsul. An in vitro release kinetic examination and comparative evaluation between submicron emulsion and polylactic acid nanocapsules of clofibride

[2] J Elsair, et al. J Pharmacol. [Effects of clofibride upon lipolysis from normal rat adipocytes in vitro (author's transl)]

[3] G P Loiseau, et al. J Pharm Pharmacol. On the metabolism of clofibride, a hypolipaemic drug

[4] C Harvengt, et al. Int J Clin Pharmacol Biopharm. Pharmacokinetic study and bioavailability of three marketed compounds releasing p-chlorophenoxyisobutyric acid (CPIB) in volunteers

[5] C Rozé, et al. Eur J Pharmacol. The effects of tiadenol, clofibrate and clofibride on bile composition in the rat

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Keywords: Clofibride supplier, inhibitors, activators

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