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CL 316243 disodium salt

Cat. No. M6613

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CL 316243 disodium salt Structure
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10mg USD 520  USD520 4-7 Days
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Biological Activity

CL 316243 disodium salt is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM); > 10000-fold selective over β1 and β2 receptors. Increases brown adipose tissue thermogenesis and metabolic rate, and decreases blood insulin and glucose levels following oral administration in vivo.

Chemical Information
Molecular Weight 465.79
Formula C20H18ClNNa2O7
CAS Number 151126-84-0
Solubility (25°C) Water 4.6 mg/mL (ultrasonic and warming and adjust pH to 12 with 1 M NaOH)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chen and Ikeda. J Neurosci. Modulation of ion channels and synaptic transmission by a human sensory neuron-specific G-protein-coupled receptor, SNSR4/mrgX1, heterologously expressed in cultured rat neurons.

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