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CID 2745687 is a specific, reversible and competitive GPR35 antagonist with a Ki of 12.8 nM. CID 2745687 (pIC50=6.27±0.08) fully reverses the agonist action of Cromolyn disodium. CID 2745687 (CID2745687; 1 mg/kg; administrated orally every day for the last 4 weeks) reverses Lodoxamide-mediated anti-fibrotic effects.
| Molecular Weight | 395.43 |
| Formula | C17H19F2N5O2S |
| CAS Number | 264233-05-8 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related GPR/FFAR Products |
|---|
| GPR84 antagonist 8
GPR84 antagonist 8 is a selective GPR84 antagonist. |
| ML191
ML-191 is an antagonist of GPR55. |
| CID1172084
CID1172084 is a selective GPR55 agonist (EC50=0.16 μM). |
| ML 145
ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM. |
| PSN 375963 hydrochloride
PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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