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Chloroquinoxaline sulfonamide

Cat. No. M30983

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Chloroquinoxaline sulfonamide Structure
Synonym:

Chloroquinoxaline; NSC-339004

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Quality Control & Documentation
Biological Activity

Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle. Antitumor activity.

Chemical Information
Molecular Weight 334.78
Formula C14H11ClN4O2S
CAS Number 97919-22-7
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ting Han, et al. Science. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15

[2] H Gao, et al. Cancer Res. Chloroquinoxaline sulfonamide (NSC 339004) is a topoisomerase IIalpha/beta poison

[3] J S Fisherman, et al. Invest New Drugs. Chloroquinoxaline sulfonamide: a sulfanilamide antitumor agent entering clinical trials

[4] R F Branda, et al. Biochem Pharmacol. Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells

[5] R F Branda, et al. Biochem Pharmacol. Immunosuppressive properties of chloroquinoxaline sulfonamide

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Keywords: Chloroquinoxaline sulfonamide, Chloroquinoxaline; NSC-339004 supplier, PROTAC, inhibitors, activators

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