Free shipping on all orders over $ 500

Chloroquinoxaline sulfonamide

Cat. No. M30983

All AbMole products are for research use only, cannot be used for human consumption.

Chloroquinoxaline sulfonamide Structure
Synonym:

Chloroquinoxaline; NSC-339004

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle. Antitumor activity.

Chemical Information
Molecular Weight 334.78
Formula C14H11ClN4O2S
CAS Number 97919-22-7
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ting Han, et al. Science. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15

[2] H Gao, et al. Cancer Res. Chloroquinoxaline sulfonamide (NSC 339004) is a topoisomerase IIalpha/beta poison

[3] J S Fisherman, et al. Invest New Drugs. Chloroquinoxaline sulfonamide: a sulfanilamide antitumor agent entering clinical trials

[4] R F Branda, et al. Biochem Pharmacol. Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells

[5] R F Branda, et al. Biochem Pharmacol. Immunosuppressive properties of chloroquinoxaline sulfonamide

Related PROTAC Products
MS4322

MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5.

xStAx-VHLL TFA

xStAx-VHLL TFA, a PROTAC, sustains β-catenin degradation and manifested strong inhibition of Wnt signaling. xStAx-VHLL TFA promotes β-catenin ubiquitination.

(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine

(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level.

MTX-23

MTX-23 is an AR-based PROTAC. MTX-23 inhibits CaP cellular proliferation by degrading AR-V7 and AR-FL. MTX-23 induces apoptosis.

YD23 

YD23 is a SMARCA2 PROTAC.

  Catalog
Abmole Inhibitor Catalog




Keywords: Chloroquinoxaline sulfonamide, Chloroquinoxaline; NSC-339004 supplier, PROTAC, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.