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Chelerythrine Chloride

Cat. No. M5319

All AbMole products are for research use only, cannot be used for human consumption.

Chelerythrine Chloride Structure
Size Price Availability Quantity
5mg USD 75  USD75 In stock
10mg USD 115  USD115 In stock
20mg USD 200  USD200 In stock
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Quality Control & Documentation
Biological Activity

Chelerythrine has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 μM) or Bad proteins and stimulates apoptosis.

Chemical Information
Molecular Weight 383.82
Formula C21H18ClNO4
CAS Number 3895-92-9
Solubility (25°C) ≥ 3.9 mg/mL in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Vieira SM, et al. Arch Biochem Biophys. Chelerythrine inhibits the sarco/endoplasmic reticulum Ca(2+)-ATPase and results in cell Ca(2+) imbalance.

[2] Bai LP, et al. Sci Rep. Recognition of chelerythrine to human telomeric DNA and RNA G-quadruplexes.

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Keywords: Chelerythrine Chloride supplier, PKC, inhibitors, activators

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